Posts Tagged ‘Genetic Material’

What makes Swine Flu so Dangerous?

Monday, July 27th, 2009
tamiflu

What makes swine flu so dangerous is that like all influenza viruses it undergoes the process of antigenic drift. This is when spot mutations occur on the genetic material that causes slight changes in the physical make-up of the virus.

These slight changes are what frustrate scientist’s attempts to create the ultimate vaccination for influenza. Due to constant changes to the protein particles of the outer coats of viruses (which the immune system is targeted for during vaccination) new vaccines are always needed to combat ever new versions of the viruses.

Swine flu is an example of such a change. But what are these changes and what parts of the virus causes the damage that destroys normal healthy cells?

The H1N1 designation of the swine flu virus gives us a clue to the inner workings of the virus. It represents the major functional proteins on its surface.

The ‘H’ stands for hemagglutinin which is a protein that binds the swine flu virus to the cell and injects its content into it.

The ‘N’ stands for neuraminidase which possesses a number of specialized enzymes that causes the infected cells to release the newly formed viruses.

All these aspects of swine flu make it potentially very dangerous. Even though the form that is currently spreading is relatively mild it could still change into a virulent strain in the next few months before winter arrives. The fact that it’s also a new disease means that there is no current vaccine for swine flu. So if it becomes more deadly, we will have no protection against it except for those provided by generic anti-viral drugs like Tamiflu and Relenza.

Tamiflu works by blocking the action of neuroamindase, obstructing the flu virus’s ability to spread from one cell to the other. But it is only effective as a treatment if it is used in the first few days during the onset of swine flu. The problem with anti-viral drugs is that it is often very difficult to diagnose the onset of swine flu. By the time the disease is identified it’s often too late to use the drugs. This is one of the reasons the effectiveness of anti-virals drugs has been called into question.

So we are currently exposed to the full potential of swine flu. We know the devastation that influenza viruses can cause, the Spanish flu pandemic infected more than one third of the world’s population and killed more than 50 million people.

We have no choice but to be vigilant to the spread of swine flu. Millions will undoubtedly catch the disease and many more will die from it. All we can do is hope that it doesn’t become more virulent and cause too much death. In its current mild form we can contain it and can control the worse of its symptoms through the use of anti-viral drugs. But if it changes we could be in trouble. Even the vaccines that are currently been developed might not be as effective if the change is marked. What we have to remember is that it is dangerous because it is so changeable and in light of this we have no choice but to treat it with extreme caution.

http://www.google.com

What makes Swine Flu so Dangerous?

What You Need To Know About Tamiflu

Monday, July 27th, 2009
tamiflu

Tamiflu, whose common scientific name is oseltamivir, is part of a family of flu fighting medicines called neuraminidase inhibitors. Tamilflu is used in the treatment of infections caused by both the influenza A and influenza B viruses. Tamiflu, which requires a prescription, can be used both to treat the flu if taken soon after symptoms appear, or to prevent the flu.

The difference between Tamiflu and a vaccine is that Tamiflu helps your immune system be in a position to fight off the advance of the viral infection, whereas a vaccine is just a straight injection of dead influenza that causes your immune system to produce antibodies to fight off the virus itself.

Tamiflu demand has skyrocketed over the past year for several reasons. There was a shortage of available flu vaccine during flu season 2005, with in some cases only enough for senior citizens or those with more vulnerable immune conditions being able to get vaccinated.

Also, the U.S. government was concerned that an outbreak of bird flu in the United States could leave the U.S. short on flu vaccines, causing them to hold back supplies just in case of an outbreak. However, the bird flu is different form human influenza.

Bird Flu is much harder to transmit than human influenza, requiring very close physical contact to spread the disease. Bird flu has been observed in countries where humans and animals are in close contact. There have been roughly 70 deaths worldwide and approximately 130 infections since 2005.

It is possible that bird flu will infect someone who is already carrying the human influenza strain, and that the two viruses will swap genetic material, causing the bird flu to spread like a deadlier version of human influenza. A highly virulent straight of bird flu could create a pandemic for the world, as did the Spanish Flu virus of the early 1900’s that killed 20 to 50 million people worldwide.

The bird flu is associated with the influenza A strain H5N1 flu virus. Although not the same as the Spanish flu virus, the current avian flu strain does share many similarities with the Spanish flu strain. Initial studies have shown that Tamiflu may be effective in helping to fight the effects of this flu virus if the medication is taken very early after flu symptoms appear. As a result, the demand for Tamiflu has skyrocketed.

A Swiss drug maker, F. Hoffman La-Roche Ltd., currently has a tight hold on the manufacturing of Tamiflu. Biolyse Pharma Corp., when turned down in its bid to try to enter the Tamiflu marketplace, had decided as of December of 2005 to attempt to mass produce several tons of shikimic acid, which is the main ingredient in Tamiflu, from the needles of discarded Christmas trees, as well as other pine, fir, and spruce trees. Such trees are the main source of shikimic acid.

Oseltamivir, sold under the brand name Tamiflu, is one of several medications approved by the U.S. Food and Drug Administration for the treatment and prevention of influenza. Flu shots are still the best way to prevent someone from developing the flu, but as of right now there is no known vaccine for the bird flu. The CDC has announced that development of a vaccine has begun.

http://www.google.com

What You Need To Know About Tamiflu

Tamiflu: Our Last Line Of Defense?

Monday, July 27th, 2009
tamiflu

Tamiflu, whose common scientific name is oseltamivir, is part of a family of flu fighting medicines called neuraminidase inhibitors. Tamilflu is used in the treatment of infections caused by both the influenza A and influenza B viruses. Tamiflu, which requires a prescription, can be used both to treat the flu if taken soon after symptoms appear, or to prevent the flu.

The difference between Tamiflu and a vaccine is that Tamiflu helps your immune system be in a position to fight off the advance of the viral infection, whereas a vaccine is just a straight injection of dead influenza that causes your immune system to produce antibodies to fight off the virus itself.

Tamiflu demand has skyrocketed over the past year for several reasons. There was a shortage of available flu vaccine during flu season 2005, with in some cases only enough for senior citizens or those with more vulnerable immune conditions being able to get vaccinated.

Also, the U.S. government was concerned that an outbreak of bird flu in the United States could leave the U.S. short on flu vaccines, causing them to hold back supplies just in case of an outbreak. However, the bird flu is different form human influenza.

Bird Flu is much harder to transmit than human influenza, requiring very close physical contact to spread the disease. Bird flu has been observed in countries where humans and animals are in close contact. There have been roughly 70 deaths worldwide and approximately 130 infections since 2005.

It is possible that bird flu will infect someone who is already carrying the human influenza strain, and that the two viruses will swap genetic material, causing the bird flu to spread like a deadlier version of human influenza. A highly virulent straight of bird flu could create a pandemic for the world, as did the Spanish Flu virus of the early 1900’s that killed 20 to 50 million people worldwide.

The bird flu is associated with the influenza A strain H5N1 flu virus. Although not the same as the Spanish flu virus, the current avian flu strain does share many similarities with the Spanish flu strain. Initial studies have shown that Tamiflu may be effective in helping to fight the effects of this flu virus if the medication is taken very early after flu symptoms appear. As a result, the demand for Tamiflu has skyrocketed.

A Swiss drug maker, F. Hoffman La-Roche Ltd., currently has a tight hold on the manufacturing of Tamiflu. Biolyse Pharma Corp., when turned down in its bid to try to enter the Tamiflu marketplace, had decided as of December of 2005 to attempt to mass produce several tons of shikimic acid, which is the main ingredient in Tamiflu, from the needles of discarded Christmas trees, as well as other pine, fir, and spruce trees. Such trees are the main source of shikimic acid.

Oseltamivir, sold under the brand name Tamiflu, is one of several medications approved by the U.S. Food and Drug Administration for the treatment and prevention of influenza. Flu shots are still the best way to prevent someone from developing the flu, but as of right now there is no known vaccine for the bird flu. The CDC has announced that development of a vaccine has begun.

http://www.google.com

Tamiflu: Our Last Line Of Defense?

What Is Tamiflu And How Does It Work?

Monday, July 27th, 2009
tamiflu

Tamiflu, whose common scientific name is oseltamivir, is part of a family of flu fighting medicines called neuraminidase inhibitors. Tamilflu is used in the treatment of infections caused by both the influenza A and influenza B viruses. Tamiflu, which requires a prescription, can be used both to treat the flu if taken soon after symptoms appear, or to prevent the flu.

The difference between Tamiflu and a vaccine is that Tamiflu helps your immune system be in a position to fight off the advance of the viral infection, whereas a vaccine is just a straight injection of dead influenza that causes your immune system to produce antibodies to fight off the virus itself.

Tamiflu demand has skyrocketed over the past year for several reasons. There was a shortage of available flu vaccine during flu season 2005, with in some cases only enough for senior citizens or those with more vulnerable immune conditions being able to get vaccinated.

Also, the U.S. government was concerned that an outbreak of bird flu in the United States could leave the U.S. short on flu vaccines, causing them to hold back supplies just in case of an outbreak. However, the bird flu is different form human influenza.

Bird Flu is much harder to transmit than human influenza, requiring very close physical contact to spread the disease. Bird flu has been observed in countries where humans and animals are in close contact. There have been roughly 70 deaths worldwide and approximately 130 infections since 2005.

It is possible that bird flu will infect someone who is already carrying the human influenza strain, and that the two viruses will swap genetic material, causing the bird flu to spread like a deadlier version of human influenza. A highly virulent straight of bird flu could create a pandemic for the world, as did the Spanish Flu virus of the early 1900’s that killed 20 to 50 million people worldwide.

The bird flu is associated with the influenza A strain H5N1 flu virus. Although not the same as the Spanish flu virus, the current avian flu strain does share many similarities with the Spanish flu strain. Initial studies have shown that Tamiflu may be effective in helping to fight the effects of this flu virus if the medication is taken very early after flu symptoms appear. As a result, the demand for Tamiflu has skyrocketed.

A Swiss drug maker, F. Hoffman La-Roche Ltd., currently has a tight hold on the manufacturing of Tamiflu. Biolyse Pharma Corp., when turned down in its bid to try to enter the Tamiflu marketplace, had decided as of December of 2005 to attempt to mass produce several tons of shikimic acid, which is the main ingredient in Tamiflu, from the needles of discarded Christmas trees, as well as other pine, fir, and spruce trees. Such trees are the main source of shikimic acid.

Oseltamivir, sold under the brand name Tamiflu, is one of several medications approved by the U.S. Food and Drug Administration for the treatment and prevention of influenza. Flu shots are still the best way to prevent someone from developing the flu, but as of right now there is no known vaccine for the bird flu. The CDC has announced that development of a vaccine has begun.

http://www.google.com

What Is Tamiflu And How Does It Work?